Comprehensive Review On The Chemistry Of 1,3,4- Oxadiazoles And Their Applications

1,3,4-Oxadiadoles have created interest in synthetic organic and medicinal chemistry as surrogates of carboxylic acid. They are an important class of heterocyclic compounds that have a wide range of pharmaceutical and biological applications. Attracted by the their broad spectrum of biological activity and as useful synthons in organic synthesis, researchers across the globe are working on this moiety and consequently have been instrumental in the advancement of 1,3,4-oxadiazole chemistry. This review article provides up to date information about developments, exploration of new methods, techniques adopted for the synthesis of 1,2,4-oxadiazoles and their varied biological activities. Now 1,2,4-oxadizoles are not limited to their synthesis and their biological applications, and is extended to study their physical properties. They are known to exhibit anticorrosion, liquid crystal, optical brightening and fluorescent properties was described.